Research Result of Huashan Hospital Hand Surgery Team Benefits Patients of Central Hemiplegia


December 21st, 2017 – Huashan Hospital hand surgery team has finished the second phase of their clinical trial on contralateral seventh cervical nerve transfer for spastic arm hemiplegia in stroke or after cerebral palsy, and published online their research result entitled “Trial of Contralateral Seventh Cervical Nerve Transfer for Spastic Arm Paralysis” on the world-famous medical journal The New England Journal of Medicine (NEJM, with an Impact Factor of 72.406). The first authors of the work are Zheng Mou-Xiong, Hua Xu-Yun, Feng Jun-Tao, Li Tie and Lu Ye-Chen from Huashan Hospital, and the corresponding author is Xu Wen-Dong 

This research result is based on the project on contralateral seventh cervical nerve transfer for brachial plexus injury initiated by Gu Yu-Dong, CAE Academician, Department Leader of Hand Surgery in Huashan Hospital, and Leader of National Clinical Research Center for Geriatrics. This new research has greatly advanced Gu’s idea and innovatively applied his method to treat patients of central hemiplegia, which is of great significance for the development of the national clinical research platform.

Central hemiplegia results from the damage of a cerebral hemisphere from stroke, traumatic brain injury, or cerebral palsy, which leads to limb movement dysfunction and sensory dysfunction. Among them, spastic arm hemiplegia is a cause of long-term disability. Patients fall victim to flexion and spasm of their paralyzed arms, and such disease impairs their daily activities, which may also burden their families and the society. For patients of central hemiplegia, though one of their cerebral hemispheres has gone through permanent damage, the other is still intact. The earlier research of the Huashan team proved that one cerebral hemisphere is capable of controlling both arms, and in their recent work, the team conducted clinical experiments and came up with a new method to restore the function of paralyzed arms in the later stage of central injury. The clinical practice worked and put forward a new theory of restoring the central function. 

Professor Xu Wen-Dong, the corresponding author of the article, Associate Dean of Huashan Hospital, Dean of Jian’an Central Hospital (to-be-established), and Chairman of Chinese Society of Hand Surgery of Chinese Medical Association, said that, the research result represents decades of efforts made by Huashan Hospital Hand Surgery Team, which not only benefits patients of spastic arm hemiplegia caused by central injury, but also develops the study on hand surgery. The research provides a new perspective for human beings to understand the brain and control it, and thus is significant scientifically and socially. 

Huashan Hospital also held a press conference of the research result on the same day when the article was published. Among the attendants of the press conference are Executive Vice-Chancellor and Dean of Shanghai Medical College Gui Yong-Hao, CAE Academician Wen Yu-Mei, CAS Academician Yang Xiong-Li, CAE Academician Zhou Liang-Fu, Dean of Huashan Hospital Ding Qiang, Secretary of Party Committee Gu Xiao-Ping and reporters from about 20 national and local mainstream media.