The recommended first-line management of advanced ovarian cancer comprises surgical staging and cytoreductive surgery followed by platinum-based chemotherapy. The response rate for first-line platinum-based chemotherapy is ~80%, although ...

METTL3 (methyltransferase-like 3) mediates the N6-methyladenosine (m6A) methylation of mRNA, which affects the stability of mRNA and its translation into protein. METTL3 also binds chromatin, but the role of METTL3 and m6A methylation in ch...

Virus infection may induce excessive interferon (IFN) responses that can lead to host tissue injury or even death. β-arrestin 2 regulates multiple cellular events through the G protein-coupled receptor (GPCR) signaling pathways. Here we de...