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DNA nanomachines reveal an adaptive energy mode in confinement-induced amoeboid migration powered by polarized mitochondrial distribution
A chemical proteomics approach for global mapping of functional lysines on cell surface of living cell
ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion
Pretraining a foundation model for generalizable fluorescence microscopy-based image restoration
Microbiota enterotoxigenic Bacteroides fragilis-secreted BFT-1 promotes breast cancer cell stemness and chemoresistance through its functional receptor NOD1
Arresting the bad seed: HDAC3 regulates proliferation of different microglia after ischemic stroke
Paternal cocaine-seeking motivation defines offspring’s vulnerability to addiction by down-regulating GABAergic GABRG3 in the ventral tegmental area.
Two-dimensional perovskite oxide as a photoactive high-κ gate dielectric
Plasma proteomic profiles predict future dementia in healthy adults
Anterior cingulate cortex projections to the dorsal medial striatum underlie insomnia associated with chronic pain
A rechargeable calcium-oxygen battery that operates at room temperature
AAV1-hOTOF Gene Therapy for Autosomal Recessive Deafness 9: a single-arm trial
Country-specific net-zero strategies of the pulp and paper industry
Structural visualization of transcription initiation in action
A novel quantitative urine LAM antigen strip for point-of-care tuberculosis diagnosis in non-HIV adults
Different projection neurons of basolateral amygdala participate in the retrieval of morphine withdrawal memory with diverse molecular pathways
Self-lifting Droplet Driven by the Solidification-induced Solutal Marangoni Flow
Plasma proteomic profiles predict individual future health risk
Asymmetric conducting route and potential redistribution determine the polarization-dependent conductivity in layered ferroelectrics
Nanomedicine for the Detection and Treatment of Ocular Bacterial Infections
ABPP-CoDEL: Activity-Based Proteome Profiling-Guided Discovery of Tyrosine-Targeting Covalent Inhibitors from DNA-Encoded Libraries
Discovery of Biaryl Amide Derivatives as Potent, Selective, and Orally Bioavailable RORγt Agonists for Cancer Immunotherapy
Assessment of visual function in blind mice and monkeys with subretinally implanted nanowire arrays as artificial photoreceptors
Context-dependent Regulation of Notch Signaling in Glial Development and Tumorigenesis
Phylogenetic evidence reveals early Kra-Dai divergence and dispersal in the late Holocene
Polycystic Ovary Syndrome Fuels Cardiovascular Inflammation and Aggravates Ischemic Cardiac Injury
ASK1-K716R reduces neuroinflammation and white matter injury via preserving blood–brain barrier integrity after traumatic brain injury
Modulating Biological Rhythms: A Noncomputational Strategy Harnessing Nonlinearity and Decoupling Frequency and Amplitude
Strong electric field force at the air/water interface drives fast sulfate production in the atmosphere
Follicle-stimulating Hormone Orchestrates Glucose-stimulated Insulin Secretion of Pancreatic Islets
Reviving Zn0 Dendrites to Electroactive Zn2+ by Mesoporous MXene with Active Edge Sites
Herbivory limits success of vegetation restoration globally
Genetic architectures of cerebral ventricles and their overlap with neuropsychiatric traits
Neurophysiological stratification of major depressive disorder by distinct trajectories
Modulating Biological Rhythms: A Noncomputational Strategy Harnessing Nonlinearity and Decoupling Frequency and Amplitude
Strong electric field force at the air/water interface drives fast sulfate production in the atmosphere
Sequencing Polymers to Enable Solid-State Lithium Batteries
Targeting neoadjuvant chemotherapy-induced metabolic reprogramming in pancreatic cancer promotes anti-tumor immunity and chemo-response
Transcriptional and epigenetic decoding of the microglial aging process
OPUS-DSD: deep structural disentanglement for cryo-EM single-particle analysis
Molecular classification of hormone receptor-positive HER2-negative breast cancer
Changing prevalence of chronic hepatitis B virus infection in China between 1973 and 2021: a systematic literature review and meta-analysis of 3740 studies and 231 million people
The brain structure, immunometabolic and genetic mechanisms underlying the association between lifestyle and depression
Decoding anxiety-impulsivity subtypes in preadolescent internalising disorders: findings from the Adolescent Brain Cognitive Development study
12-inch growth of uniform MoS2 monolayer for integrated circuit manufacture
Host traits shape virome composition and virus transmission in wild small mammals
Optimized glycemic control of type 2 diabetes with reinforcement learning: a proof-of-concept trial
Structure evolution at the gate-tunable suspended graphene-water interface
TERT accelerates BRAF mutant-induced thyroid cancer dedifferentiation and progression by regulating ribosome biogenesis
Biallelic variants in RBM42 cause a multisystem disorder with neurological, facial, cardiac, and musculoskeletal involvement
CD300ld on neutrophils is required for tumour-driven immune suppression
TRPM7 kinase activity induces amyloid-β degradation to reverse synaptic and cognitive deficits in mouse models of Alzheimer’s disease
Evidence for non-traditional mcr-containing archaea contributing to biological methanogenesis in geothermal springs
Neoadjuvant adebrelimab in locally advanced resectable esophageal squamous cell carcinoma: a phase 1b trial
Accelerating the energy transition towards photovoltaic and wind in China
Prioritizing genes associated with brain disorders by leveraging enhancer-promoter interactions in diverse neural cells and tissues
Enantiocontrolled macrocyclization by encapsulation of substrates in chiral capsules
Tipping points detection using reservoir computing
Designing F/P Hybrid Polymer as Ultrastable Cationic Shielding Interphase for High-Performance Lithium Metal Batteries
R-loop dependent promoter-proximal termination ensures genome stability
Emerging Therapies in Cancer Metabolism
CRIP1 fosters MDSC trafficking and resets tumour microenvironment via facilitating NF-κB/p65 nuclear translocation in pancreatic ductal adenocarcinoma
Neurodevelopmental risk and adaptation as a model for comorbidity among internalizing and externalizing disorders: genomics and cell-specific expression enriched morphometric study
Enterotypes of the human gut mycobiome
Association between vmPFC gray matter volume and smoking initiation in adolescents
Rare Loss-of-Function variants reveal threshold and multifactorial inheritance of Dextrocardia
Selective treatment de-intensification by reducing radiation dose and omitting concurrent chemotherapy based on response to induction chemotherapy in HPV-associated oropharyngeal squamous cell carcinoma: the preliminary results of a single-arm, phase
A putative loop connection between VTA dopamine neurons and nucleus accumbens encodes positive valence to compensate for hunger
HSPB2 facilitates neural regeneration through autophagy for sensorimotor recovery after traumatic brain injury
Effects of urban living environments on mental health in adults
Ccdc85c-Par3 condensates couple cell polarity with Notch to control neural progenitor proliferation
A neural circuit for regulating a behavioral switch in response to prolonged uncontrollability in mice
Oxytocin Improves Intracerebral Hemorrhage Outcomes by Suppressing Neuronal Pyroptosis and Mitochondrial Fission
Highly multiplexed bioactivity screening reveals human and microbiota metabolome-GPCRome interactions
A Pangenome Reference of 36 Chinese populations
Effect of interval between neoadjuvant chemoradiotherapy and surgery on oncological outcomes in poor responders with locally advanced rectal cancer: a retrospective cohort study
A CPG-based versatile control framework for metameric earthworm-like robotic locomotion
CCL19+ dendritic cells potentiate clinical benefit of anti-PD-(L)1 immunotherapy in triple-negative breast cancer
Imaging of pH distribution inside individual microdroplet by stimulated Raman microscopy
Molecular Profiling Provides Clinical Insights Into Targeted and Immunotherapies as Well as Colorectal Cancer Prognosis
Visualizing slow internal relaxations in a two-dimensional glassy system
Muscle PARP1 inhibition extends lifespan through AMPKα PARylation and activation in Drosophila
Covalent bonding strategy to enable non-volatile organic cation perovskite for highly stable and efficient solar cells
A shared neural basis underlying psychiatric comorbidity
Controlled radical copolymerization of fluoroalkenes by using light-driven redox-relay catalysis
Signal propagation in complex networks
Structural insights into RNase J that plays an essential role in Mycobacterium tuberculosis RNA metabolism
Early Detection of Molecular Residual Disease and Risk Stratification for Stage I to III Colorectal Cancer via Circulating Tumor DNA Methylation
INTAC endonuclease and phosphatase modules differentially regulate transcription by RNA polymerase II
Toward antifragility: Social defeat stress enhances learning and 3 memory in young mice via hippocampal SNAP-25
Understanding the genetics of human infertility
A self-charging salt water battery for antitumor therapy
The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models
The Doping Effect on the Intrinsic Ferroelectricity in Hafnium Oxide-Based Nano-Ferroelectric Devices
Neuroimaging biomarkers define neurophysiological subtypes with distinct trajectories in schizophrenia
Recursive traffic percolation on urban transportation systems featured
Subtyping-based platform guides precision medicine for heavily pretreated metastatic triple-negative breast cancer: The FUTURE phase II umbrella clinical trial
Short-term acute bright light exposure induces a prolonged anxiogenic effect in mice via a retinal ipRGC-CeA circuit
An ultrafast bipolar flash memory for self-activated in-memory computing
